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Please do not use these instructions. All software and documentation is being migrated to github. Also please update any bookmarks, as this site will disappear shortly.


OpenMIMS is an ImageJ plugin to open, process and analyze images captured with NanoSIMS 50 & 50L secondary ion mass spectrometers (Cameca). The plugin has been developed at the National Resource for Imaging Mass Spectrometry (NRIMS,, an NIH-supported National Resource developing Multi-isotope Imaging Mass Spectrometry (MIMS) for biomedical research. Images and/or stacks of images for up to 7 different isotopes can be opened, analyzed and saved. All metadata saved in the original file are preserved. Image ratios and Hue-Saturation-Intensity (HSI) maps of any combination of isotopes can be displayed and data from any number of Regions of Interest (ROIs) extracted, analyzed and tabulated for single images or entire stacks.


OpenMIMS Manual

unu Commands

NRRD Mosaics

Nrrd File Format

Sample Data

Main NRIMS Website